RESIST-5 O.O.K.N.V. This new immunochromatography test, made of two cassettes, allows the identification of OXA-48-like, OXA-163, KPC, NDM and VIM carbapenemases from culture.
Why is OXA-163 important?
A major difference between the OXA-48 and the OXA-163 carbapenemase is that the OXA 48 is a carbapenemase with a middle or high hydrolysis activity and the OXA 163 is carbapenemase without or with a weak hydrolysis activity.
A major difference between the OXA-48 and the OXA-163 carbapenemase is that the OXA 48 is a carbapenemase with a middle or high hydrolysis activity and the OXA 163 is carbapenemase without or with a weak hydrolysis activity.
.The main consequence of this difference is that a patient, carrier of OXA 163, could be treated with carbapenem whilst a patient carrier of an OXA 48 would not be treated with a carbapenem.
It is thus important for the clinician that the laboratory uses a test that has the capability to differentiate between an OXA 48 and an OXA 163 strain.
If a diagnostic test is identifying OXA-163 as an OXA-48 the validity of the result and the accuracy of the clinical guidance are questionable.
It is thus important for the clinician that the laboratory uses a test that has the capability to differentiate between an OXA 48 and an OXA 163 strain.
If a diagnostic test is identifying OXA-163 as an OXA-48 the validity of the result and the accuracy of the clinical guidance are questionable.
Is mis-identifying OXA-163 as OXA-48-like a false positive result?
Is OXA-163 common?
Download this file for snippets from relevant publications and their reference.
Is OXA-163 common?
Download this file for snippets from relevant publications and their reference.
| oxa163_sway_refs.pdf |
