The rapid and simple RESIST method

RESIST-5 O.O.K.N.V. - Publications
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• P0293 – Reduction in the detection time of OXA-48, OXA-163 and KPC carbapenemases performed with a novel immunochromatographic lateral flow assay from 2-hour-old cultures (early cultures).
F. Pasteran, L. Denorme, Q. Gilleman, S. Gomez, E. Albornoz, Y. Glupczynski, P. Bogaerts, P. Mertens and A. Corso.
27th European Congress of Clinical Microbiology and Infectious Diseases, Infectious Diseases April 22 – 25, 2017
 Poster


• Rapid Identification of OXA-48 and OXA-163 Subfamilies in Carbapenem-Resistant Gram-Negative Bacilli with a Novel Immunochromatographic Lateral Flow Assay.

Pasteran F, Denorme L, Ote I, Gomez S, De Belder D, Glupczynski Y, Bogaerts P, Ghiglione B, Power P, Mertens P, Corso A.
J Clin Microbiol. 2016 Nov;54(11):2832-2836. Epub 2016 Aug 17.
Abstract
TWe assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allowed rapid (less than 4 min) and reliable direct confirmation of OXA-163- and/or OXA-48-like enzymes (with 100% sensitivity and 100% specificity) from cultured colonies that were recovered from both solid medium and spiked blood culture bottles.
https://www.ncbi.nlm.nih.gov/pubmed/27535687