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Food for thought
Carbapenemase screening - Fast and expensive or cheap and slow?  

This exercise in mathematical modelling compares direct PCR screening (half a day) with culture + PCR which required 2.5 days.  Taking into account 'days at risk' (when a patient with CP-CRE was not detected and hence not isolated) , total cost and average cost per CP-CRE risk day averted the slower option provided optimal balance of cost and risk days averted.

Of course now RESIST offers culture + identification in 24 hours at considerable less cost than culture + PCR the balance has swung further in favour of culture + identification.


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fast_and_expensive.pdf
File Size: 1246 kb
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Counting the cost of a CPE outbeak.

An outbreak of a NDM Klebsiella affecting 40 patients in a group of five hospitals across three sites in West London cost 1.1m euro over 10 months .  Less than 10% was allocated to  extra laboratory expenditure.

This is the kind of cost that effective patient screening is guarding against.
otter_cost_ofcpe.pdf
File Size: 413 kb
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Announcement of change from PCR to RESIST in the preferred screening algorithm 

An update  announcement to the detection of carbapenemase-producing Enterobacteriaceae (CPE) in Microbiology at North West London Pathology

charing_cross_3.pdf
File Size: 99 kb
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​Identifying the 'Big Four' carbapenemases in a routine laboratory
​
- Pathology in Practice
ppbiocon_pipapr18__1_.pdf
File Size: 143 kb
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OXA-48-,KPC-&NDM-type carbapenemase-producing organismdetection
- Pathology in Practice
royal_free.pdf
File Size: 102 kb
File Type: pdf
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  • Home page
  • Antibiotic Resistance
  • CHROMagar
  • Coris RESIST
  • Coris BioConcept ICT
  • Gonogen
  • MICROBIOLOGICS
  • MICRONAUT Broth Microdilution
    • yeasts&moulds
  • Mycology
  • Rosco Neo-sensitabs
  • REAL saliva
  • Rosco Phenotyping
  • Sifin Antisera
  • About
  • contact