Food for thought
Carbapenemase screening - Fast and expensive or cheap and slow?
This exercise in mathematical modelling compares direct PCR screening (half a day) with culture + PCR which required 2.5 days. Taking into account 'days at risk' (when a patient with CP-CRE was not detected and hence not isolated) , total cost and average cost per CP-CRE risk day averted the slower option provided optimal balance of cost and risk days averted.
Of course now RESIST offers culture + identification in 24 hours at considerable less cost than culture + PCR the balance has swung further in favour of culture + identification.
This exercise in mathematical modelling compares direct PCR screening (half a day) with culture + PCR which required 2.5 days. Taking into account 'days at risk' (when a patient with CP-CRE was not detected and hence not isolated) , total cost and average cost per CP-CRE risk day averted the slower option provided optimal balance of cost and risk days averted.
Of course now RESIST offers culture + identification in 24 hours at considerable less cost than culture + PCR the balance has swung further in favour of culture + identification.
| fast_and_expensive.pdf |
Counting the cost of a CPE outbeak.
An outbreak of a NDM Klebsiella affecting 40 patients in a group of five hospitals across three sites in West London cost 1.1m euro over 10 months . Less than 10% was allocated to extra laboratory expenditure.
This is the kind of cost that effective patient screening is guarding against.
An outbreak of a NDM Klebsiella affecting 40 patients in a group of five hospitals across three sites in West London cost 1.1m euro over 10 months . Less than 10% was allocated to extra laboratory expenditure.
This is the kind of cost that effective patient screening is guarding against.
| otter_cost_ofcpe.pdf |
Announcement of change from PCR to RESIST in the preferred screening algorithm
An update announcement to the detection of carbapenemase-producing Enterobacteriaceae (CPE) in Microbiology at North West London Pathology
An update announcement to the detection of carbapenemase-producing Enterobacteriaceae (CPE) in Microbiology at North West London Pathology
| charing_cross_3.pdf |
Identifying the 'Big Four' carbapenemases in a routine laboratory
- Pathology in Practice
| ppbiocon_pipapr18__1_.pdf |
OXA-48-,KPC-&NDM-type carbapenemase-producing organismdetection
- Pathology in Practice
- Pathology in Practice
| royal_free.pdf |
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