resistance & M.I.C.
Streptococcus pneumoniae no longer has predictable antibiotic susceptibility. Strains with low-level penicillin resistance still respond to penicillin in respiratory tract infections and bacteraemia, but not in meningitis.
Where Oxacillin 1 µg is used as a screen for beta-lactam resistance EUCAST recommends an MIC is obtained where the zone is <20mm
MIC for all except colistin & bacitracin
H. influenzae & broth microdilution
Comparative testing between BMD and gradient diffusion testing has highlighted concerns about the reliability of gradient diffusion tests for determining the MIC of H. influenza
A EUCAST poster at ECCMID 2016 stated he correlation between gradient test MICs and BMD is poor for some antibiotics
P805 ECCMID 2016