Streptococcus pneumoniae
resistance & M.I.C. Streptococcus pneumoniae no longer has predictable antibiotic susceptibility. Strains with low-level penicillin resistance still respond to penicillin in respiratory tract infections and bacteraemia, but not in meningitis. Where Oxacillin 1 µg is used as a screen for beta-lactam resistance EUCAST recommends an MIC is obtained where the zone is <20mm |
Antibiotic Panel
Amoxycillin/Clavulanate Ampicillin Bacitracin Ceftriaxon Cefuroxim Ciprofloxacin Clarithromycin Clindamycin Colistin Doxycyclin Erythromycin Imipenem Moxifloxacin Penicillin G MIC for all except colistin & bacitracin
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H. influenzae & broth microdilution
Comparative testing between BMD and gradient diffusion testing has highlighted concerns about the reliability of gradient diffusion tests for determining the MIC of H. influenza A EUCAST poster at ECCMID 2016 stated he correlation between gradient test MICs and BMD is poor for some antibiotics P805 ECCMID 2016 | ||||
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