MIC determination of critical important backup antibiotics used for clinically important non-fermenting pathogens

In recent years, there has been a dramatic increase in multi-drug resistance (MDR) amongst gram-negative pathogens like Pseudomonas aeruginosa, Acinetobacter baumannii and other non-fermenting organisms. This has impacted the treatment of both hospital and community acquired infections. Therefore, accurate and reliable MIC determination is crucial for a successful antimicrobial therapy.


The routine MIC plate MICRONAUT-S Pseudomonas MIC provides an extended spectrum of standard and critical important backup antibiotics used for treatment of infections caused by multi-drug resistant non-fermenting pathogens. It enables MIC determination of antibiotics like piperacillin-tazobactam, ceftazidime-avibactam, ceftolozane-tazobactam, meropenem, tigecyclin and colistin in a single test run. MIC values are interpreted according to currently valid EUCAST breakpoints.

MIC plate for AST of multi-drug resistant non-fermenting bacteria (MDR phenotype)
The MICRONAUT-S Pseudomonas MIC test plate offers a range of features and benefits relating to the phenotypic quantification of MIC values for critically important backup antibiotics used for treatment of bacterial infections caused by non-fermenting bacteria.

• AST is carried out by broth microdilution method
• Resistance determination of clinically relevant non-fermenting organisms (Pseudomonas aeruginosa, Acinetobacter baumannii, Stenotrophomonas maltophilia and other non-fermenters) against antibiotics and antibiotic combinations
• AST for highly effective and critically important backup antibiotics and antibiotic combinations like piperacillin-tazobactam, ceftazidime-avibactam, ceftolozane-tazobactam or tigecycline in a single test run
• Accurate and reliable AST for colistin
• Analysis and interpretation of MIC values after visual or automated reading according to EUCAST standard

​Antibiotics
Including critically important antibiotics like ceftazidime-avibactam, ceftolozane-tazobactam
and colistin, showing good antimicrobial efficacy against gram-negative bacteria.

Amikacin                                   Gentamicin
Aztreonam                                 Imipenem
Cefepime                                   Levofloxacin
Ceftazidime                               Meropenem
Ceftazidime-avibactam           Piperacillin  
Ceftolozane- tazobactam       Piperacillin- tazobactam
 Ciprofloxacin                          Tobramycin
  Colistin                                    Trimethoprim- sulfamethoxazole

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