Phenotypic detection of clinically relevant cephalosporinases and carbapenemases
In recent years there has been an increase in multi-drug resistance (MDR) amongst gram-negative pathogens. This has impacted both hospital and community acquired infections.
The MICRONAUT-S MDR MRGN Screening plate provides an extended spectrum of critically important back-up antibiotics and meropenem screening concentrations for an improved detection of OXA-48-like type D carbapenemases. It also offers an extended spectrum of antibiotics by introduction of the novel antibiotic combinations ceftazidime-avibactam and ceftolozane-tazobactam.
MIC plate for AST of multi-drug resistant gram-negative bacteria (MDR phenotype)
The MICRONAUT-S MDR MRGN Screening plate offers a range of features and benefits relating to the phenotypic detection of clinically relevant resistance mechanisms.
Resistance determination of all relevant gram-negative bacteria (Enterobacteria, Aeromonas, non-fermenters) against antibiotics and antibiotics combinations in a standard microdilution procedure
AST against the novel antibiotic combinations ceftazidime-avibactam and ceftolozane-tazobactam
Phenotypical detection of MBL (metallo-ß-lactamases) by resistance determination against meropenem as a mono substance and in combination with the divalent cationic chelator EDTA
Phenotypical detection of KPC (Klebsiella pneumoniae carbapenemase) by resistance determination against meropenem as a mono substance and in combination with 3-Amino-Phenyl-Borate (3-APB)
Phenotypical detection of AMP-C (Aminopenicillin inactivating cephalosporinase) by the susceptibility testing with 3 extended spectrum cephalosporins and their combination with (3-APB)
Detection of OXA-48-like type D carbapenemases based on the determination of temocillin high-level resistance
Detection of low-level carbapenem resistance by introduction of meropenem screening concentrations
Analysis and interpretation after visual or automated reading according to EUCAST or CLSI standard
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