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Colistin M.I.C
Colistin (polymyxin E) MIC determination is associated with several methodological issues. The CLSI-EUCAST joint Polymyxin Breakpoints Working Group recommend that only broth microdilution is suitable for determining Colistin MIC .
EUCAST has issued warnings about batches of gradient diffusion products
EUCAST has issued warnings about batches of gradient diffusion products
MICRONAUT's broth microdilution Colistin MIC has been on the market for many years and conforms to ISO20776-1:2006. The strip comes in packs of 5 plates, each plate has 8 removable strips of 12 wells, giving each pack 40 tests.
from the EUCAST website
Summary of results for all commercial BMD methods
Essential agreement (MICs within ± 1 dilution of reference MIC):
from the EUCAST website
Summary of results for all commercial BMD methods
Essential agreement (MICs within ± 1 dilution of reference MIC):
- Sensititre (Thermo Fisher Scientific): 96%
- MICRONAUT-S (Merlin Diagnostika): 96%
- MICRONAUT MIC-Strip (Merlin Diagnostika): 99%
- SensiTest (Liofilchem): 88%
- UMIC (Biocentric): 82%
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